C57BL/6JGpt-Gpnmbem1Cflox/Gpt
Gpnmb-flox|Strain NO.T008779
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Gpnmbem1Cflox/Gpt |
| Strain Number: | T008779 |
| Official Symbol: | Gpnmb |
| Strain Strategy: | T008779.Gpnmb Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | glycoprotein (transmembrane) nmb |
| Also Known As: | DC-HIL,Dchil,ipd |
| NCBI Number: | 93695 |
| MGI Number: | 1934765 |
| Chromosome: | 6 |
| Distance Between Two Loxps: | 10615bp |
| Research Areas: | Metabolic research,immune system,integument,Tumor research,nervous system,Signal Transduction,vision/eye,Cell Proliferation,Cell death,Protein metabolism,Physiological system,behavior/neurological,Cell biology,Molecular biology,pigmentation,Cytoplasmic vesicle,endosome,Organelles membrane |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T008779.Gpnmb Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. GPNMB disrupts SNARE complex assembly to maintain bacterial proliferation within macrophages. Cell Mol Immunol (2025) |