C57BL/6JGpt-Havcr1em1Cflox/Gpt
Mouse Model: Havcr1-flox
Strain Number: T008757
Conditional knockout (cKO)
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Havcr1em1Cflox/Gpt |
| Strain Number: | T008757 |
| Official Symbol: | Havcr1 |
| Strain Strategy: | Log in to read more |
| Official Full Name: | hepatitis A virus cellular receptor 1 |
| Also Known As: | AI503787,KIM-1,TIM-1,Tim1,Timd1 |
| NCBI Number: | 171283 |
| MGI Number: | 2159680 |
| Chromosome: | 11 |
| Distance Between Two Loxps: | 20195bp |
| Research Areas: | immune system,Physiological system,respiratory system,hematopoietic system,Molecular biology,Lipid binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | Log in to read more |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury. Nat Commun (2023)2. The HAVCR1-centric host factor network drives Zika virus vertical transmission. Cell Rep (2025)3. A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury. Science advances (2025) |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.