C57BL/6JGpt-Asf1aem1Cflox/Gpt

Mouse Model: Asf1a-flox
Strain Number: T008410

Conditional knockout (cKO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Asf1aem1Cflox/Gpt
Strain Number: T008410
Official Symbol: Asf1a
Strain Strategy: T008410.Asf1a Cas9-CKO Strain Strategy.pdf
Official Full Name: anti-silencing function 1A histone chaperone
Also Known As: 2310079C17Rik,C79052
NCBI Number: 66403
MGI Number: 1913653
Chromosome: 10
Distance Between Two Loxps: 946bp
Research Areas: Developmental Biology,cell differentiation,embryo,growth/size/body,mortality/aging,nervous system,Cell biology,cellular,cell nucleus
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T008410.Asf1a Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. ASF1A-dependent P300-mediated histone H3 lysine 18 lactylation promotes atherosclerosis by regulating EndMT. Acta Pharmaceutica Sinica B (2024)

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.