C57BL/6JGpt-Mir378aem1Cflox/Gpt
Mir378a-flox|Strain NO.T007903
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Mir378aem1Cflox/Gpt |
| Strain Number: | T007903 |
| Official Symbol: | Mir378a |
| Strain Strategy: | T007903.Mir378a Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | microRNA 378a |
| Also Known As: | Mir378,Mirn378,mmu-mir-378,mmu-mir-378a |
| NCBI Number: | 723889 |
| MGI Number: | 3617791 |
| Chromosome: | 18 |
| Distance Between Two Loxps: | 3909bp |
| Research Areas: | Metabolic research,adipose tissue,homeostasis/metabolism,Developmental Biology,growth/size/body,Physiological system,integument,digestive/alimentary system,liver/biliary system,Cell biology,cellular,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T007903.Mir378a Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Macrophage-derived extracellular vesicles regulate skeletal stem/progenitor Cell lineage fate and bone deterioration in obesity. Bioact Mater (2024)2. Aged bone marrow macrophages drive systemic aging and age-related dysfunction via extracellular vesicle-mediated induction of paracrine senescence. Nature Aging (2024) |