C57BL/6JGpt-Aars2em1Cflox/Gpt
Aars2-flox|Strain NO.T008338
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Aars2em1Cflox/Gpt |
| Strain Number: | T008338 |
| Official Symbol: | Aars2 |
| Strain Strategy: | T008338.Aars2 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | alanyl-tRNA synthetase 2, mitochondrial |
| Also Known As: | Aarsl,AlaRS,Gm89 |
| NCBI Number: | 224805 |
| MGI Number: | 2681839 |
| Chromosome: | 17 |
| Distance Between Two Loxps: | 10121bp |
| Research Areas: | Metabolic research,Protein metabolism,Developmental Biology,embryo,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,behavior/neurological,Physiological system,integument,pigmentation,cardiovascular system,hematopoietic system,Cell biology,Mitochondrial research,Molecular biology,hydrolytic enzyme,ligase,RNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T008338.Aars2 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation2. AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases |
| Gene Family: | Aminoacyl tRNA synthetases, Class II |