C57BL/6JGpt-Ace2em1Cin(hACE2)/Gpt

hACE2(all humanization)|Strain NO.T037659

Knockin (KI)

  • Product Type:
  • Quantity: - +
  • Sex:
  • Age:
  • Genotype:
BASIC INFORMATION
Strain Name: C57BL/6JGpt-Ace2em1Cin(hACE2)/Gpt
Strain Number: T037659
Official Symbol: ACE2,Ace2,hACE2
Strain Strategy: T037659.B6-HuACE2_FL strain info.pdf
Official Full Name: angiotensin I converting enzyme 2,angiotensin I converting enzyme
Also Known As: ACEH,2010305L05Rik
NCBI Number: 5927270008
Research Areas: Humanized model,Gene humanization model
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockin (KI)
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry2. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model3. Non-adjuvanted interferon-armed RBD protein nasal drops protect airway infection from SARS-CoV-2