C57BL/6JGpt-Ace2em1Cin(hACE2)/Gpt
hACE2(all humanization)|Strain NO.T037659
Knockin (KI)
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BASIC INFORMATION
Strain Name: | C57BL/6JGpt-Ace2em1Cin(hACE2)/Gpt |
Strain Number: | T037659 |
Official Symbol: | ACE2,Ace2,hACE2 |
Strain Strategy: | T037659.B6-HuACE2_FL strain info.pdf |
Official Full Name: | angiotensin I converting enzyme 2,angiotensin I converting enzyme |
Also Known As: | ACEH,2010305L05Rik |
NCBI Number: | 5927270008 |
Research Areas: | Humanized model,Gene humanization model |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Knockin (KI) |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry2. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model3. Non-adjuvanted interferon-armed RBD protein nasal drops protect airway infection from SARS-CoV-2 |