C57BL/6JGpt-Ace2em1Cin(hACE2)/Gpt
Mouse Model: hACE2(all humanization)
Strain Number: T037659
Knockin (KI)
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Ace2em1Cin(hACE2)/Gpt |
| Strain Number: | T037659 |
| Official Symbol: | ACE2,Ace2,hACE2 |
| Strain Strategy: | T037659.B6-HuACE2_FL strain info.pdf |
| Official Full Name: | angiotensin I converting enzyme 2,angiotensin I converting enzyme |
| Also Known As: | ACEH,2010305L05Rik |
| NCBI Number: | 5927270008 |
| Research Areas: | Humanized model,Gene humanization model |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockin (KI) |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry. Signal transduction and targeted therapy (2021)2. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model. Science (2021)3. Non-adjuvanted interferon-armed RBD protein nasal drops protect airway infection from SARS-CoV-2. Cell Discov (2022) |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.