C57BL/6JGpt-Ucp1em13Cd5701/Gpt
Mouse Model: Ucp1-KO
Strain Number: T037633
Knockout (KO)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Ucp1em13Cd5701/Gpt |
| Strain Number: | T037633 |
| Official Symbol: | Ucp1 |
| Strain Strategy: | T037633.Ucp1 Cas9-KO Strategy-EN.pdfT037633.Ucp1-KO strain info.pdf |
| Official Full Name: | uncoupling protein 1 (mitochondrial, proton carrier) |
| Also Known As: | AI385626,Slc25a7,Ucp |
| NCBI Number: | 22227 |
| MGI Number: | 98894 |
| Chromosome: | 8 |
| Deletion (size): | -5701bp |
| Research Areas: | Metabolic research,adipose tissue,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,nervous system,vision/eye,Cell biology,Mitochondrial research,cellular,Cell localization,cytomembrane,Molecular biology,DNA transcription,Lipid binding protein,transporter |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T037633.Ucp1 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Mirabegron displays anticancer effects by globally browning adipose tissues. Nat Commun (2023)2. Distinct effects of physical and functional ablation of brown adipose tissue on T3-dependent pathological cardiac remodeling. Biochem Biophys Res Commun (2024)3. Uncoupling protein 1-mediated protective effects of β3-adrenergic receptor agonist on kidney fibrosis via promoting adipose tissue browning in diabetic mice. Int J Biol Macromol (2025) |
| Gene Family: | Solute carriers |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.