huCD34+HSC-NOD/ShiLtJGpt-Prkdcem26Cd52Il2rgem26Cd22/Gpt(CH)
huHSC-NCG(CH)|Strain NO.T037620
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | huCD34+HSC-NOD/ShiLtJGpt-Prkdcem26Cd52Il2rgem26Cd22/Gpt(CH) |
| Strain Number: | T037620 |
| Official Symbol: | Prkdc,Il2rg |
| Strain Strategy: | T037620.huHSC-NCG(CH) Strain info.pdf |
| Official Full Name: | protein kinase, DNA activated, catalytic polypeptide,interleukin 2 receptor, gamma chain |
| Also Known As: | p460; scid; slip; DNAPK; DNPK1; HYRC1; XRCC7; dxnph; DOXNPH; DNAPDcs; AI326420; AU019811; DNA-PKcs,gc; p64; [g]c; CD132; gamma(c) |
| NCBI Number: | 1909016186 |
| Research Areas: | Humanized model,Humanization of the immune system,Immunodeficiency |
| Strain Background: | [N000235] NOD/ShiLtJGpt |
| Modification Type: | Knockout (KO) |
| Inventory Status: | Live |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy2. Reprograming immunosuppressive microenvironment by eIF4G1 targeting to eradicate pancreatic ductal adenocarcinoma3. Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2 |