C57BL/6JGpt-Tcf21em1Cflox/Gpt
Mouse Model: Tcf21-flox
Strain Number: T013083
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Tcf21em1Cflox/Gpt |
| Strain Number: | T013083 |
| Official Symbol: | Tcf21 |
| Strain Strategy: | T013083.Tcf21 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | transcription factor 21 |
| Also Known As: | Pod-1,Pod1,bHLHa23,capsulin,epc,epicardin |
| NCBI Number: | 21412 |
| MGI Number: | 1202715 |
| Chromosome: | 10 |
| Distance Between Two Loxps: | 9363bp |
| Research Areas: | Metabolic research,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,mortality/aging,immune system,Physiological system,integument,cardiovascular system,Muscle ,respiratory system,reproductive system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,Cell biology,cellular,cell nucleus,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T013083.Tcf21 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs. Acta Pharmacol Sin (2023) |
| Gene Family: | Basic helix-loop-helix proteins |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.