Myd88-flox|Strain NO.T009598

Conditional knockout (cKO)

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Strain Name: C57BL/6JGpt-Myd88em1Cflox/Gpt
Strain Number: T009598
Official Symbol: Myd88
Strain Strategy: T009598.Myd88 Cas9-CKO Strategy-EN.pdf
Official Full Name: myeloid differentiation primary response gene 88
NCBI Number: 17874
MGI Number: 108005
Chromosome: 9
Distance Between Two Loxps: 3600bp
Research Areas: Metabolic research,Developmental Biology,immune system,cardiovascular system,Tumor research,nervous system,Signal Transduction,skeleton,vision/eye,hearing/ear,respiratory system,adipose tissue,Cell Proliferation,Cell death,DNA transcription,digestive/alimentary system,Protein metabolism,liver/biliary system,renal/urinary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,growth/size/body,hematopoietic system,Cell localization,cell nucleus,Organelles membrane,synapse
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T009598.Myd88 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response2. Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88-Dependent Inflammation
Gene Family: My-T-BRC complexTIR domain containing