C57BL/6JGpt-Edaem1Cd/Gpt

Mouse Model: Eda-KO
Strain Number: T017710

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Edaem1Cd/Gpt
Strain Number: T017710
Official Symbol: Eda
Strain Strategy: T017710.Eda Cas9-KO Strategy-EN.pdf
Official Full Name: ectodysplasin-A
Also Known As: EDA1,Ed1,Eda-A1,Eda-A2,HED,Ta,Tnlg7c,XLHED,tabby
NCBI Number: 13607
MGI Number: 1195272
Chromosome: X
Deletion (size): -3248bp
Research Areas: Developmental Biology,cell differentiation,growth/size/body,immune system,nervous system,vision/eye,Physiological system,integument,pigmentation,cardiovascular system,skeleton,craniofacial ,respiratory system,reproductive system,digestive/alimentary system,renal/urinary system,endocrine/exocrine glands,limbs/digits/tail,Cell biology,Organelles membrane,Molecular biology,Signal Transduction
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Inventory Status: Cryopreserved
Sale Status: IP: Pre-Sale
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. EDA ligand triggers plasma membrane trafficking of its receptor EDAR via PKA activation and SNAP23-containing complexes. Cell Biosci (2023)
Gene Family: MicroRNA protein coding host genesTumor necrosis factor superfamily

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.