C57BL/6JGpt-Gsdmcem1Cd2104in1/Gpt
Gsdmc-KO|Strain NO.T016981
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Gsdmcem1Cd2104in1/Gpt |
| Strain Number: | T016981 |
| Official Symbol: | Gsdmc |
| Strain Strategy: | T016981.Gsdmc Cas9-KO Strategy-EN.pdf |
| Official Full Name: | gasdermin C |
| Also Known As: | Gsdmc1,Mlze |
| NCBI Number: | 83492 |
| MGI Number: | 1933176 |
| Chromosome: | 15 |
| Deletion (size): | -2104bp+1bp |
| Research Areas: | Developmental Biology,embryo,mortality/aging,nervous system,behavior/neurological,Physiological system,skeleton,limbs/digits/tail,Cell biology,Cell death,Cytoskeleton,Mitochondrial research,Organelles membrane,Molecular biology,Lipid binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T016981.Gsdmc Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Caspase-6/Gasdermin C-Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2-Dependent Recruitment of Myeloid-Derived Suppressor Cells. Adv Sci (Weinh) (2025) |