C57BL/6JGpt-Casq1em7Cd4231/Gpt

Mouse Model: Casq1-KO
Strain Number: T017350

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Casq1em7Cd4231/Gpt
Strain Number: T017350
Official Symbol: Casq1
Strain Strategy: T017350.Casq1 Cas9-KO Strategy-EN.pdf
Official Full Name: calsequestrin 1
Also Known As: CSQ,CSQ-1,CSQ1,sCSQ
NCBI Number: 12372
MGI Number: 1309468
Chromosome: 1
Deletion (size): -4231bp
Research Areas: Metabolic research,Developmental Biology,nervous system,Signal Transduction,skeleton,Muscle ,Mitochondrial research,Physiological system,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,growth/size/body,hematopoietic system,Cell localization,endoplasmic reticulum,Golgi apparatus,Organelles membrane
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T017350.Casq1 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Critical role of Znhit1 for postnatal heart function and vacuolar cardiomyopathy. JCI insight (2022)
Gene Family: Protein disulfide isomerases

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.