C57BL/6JGpt-Prss1em1Cd/Gpt

Mouse Model: Prss1-KO
Strain Number: T013943

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Prss1em1Cd/Gpt
Strain Number: T013943
Official Symbol: Prss1
Strain Strategy: T013943.Prss1 Cas9-KO Strategy-EN.pdf
Official Full Name: protease, serine 1 (trypsin 1)
Also Known As: Try-1,Try1,Trygn16
NCBI Number: 114228
MGI Number: 98839
Chromosome: 6
Research Areas: Metabolic research,Protein metabolism,immune system,Physiological system,cardiovascular system,reproductive system,digestive/alimentary system,endocrine/exocrine glands,Cell biology,cellular,Molecular biology,hydrolytic enzyme
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Inventory Status: Cryopreserved
Sale Status: IP: Pre-Sale
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Nature cell biology (2022)

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.