C57BL/6JGpt-Cmtm6em4Cd13539in1/Gpt
Mouse Model: Cmtm6-KO
Strain Number: T013922
Knockout (KO)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Cmtm6em4Cd13539in1/Gpt |
| Strain Number: | T013922 |
| Official Symbol: | Cmtm6 |
| Strain Strategy: | T013922.Cmtm6 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | CKLF-like MARVEL transmembrane domain containing 6 |
| Also Known As: | 2810051A14Rik,AA536733,Cklfsf6 |
| NCBI Number: | 67213 |
| MGI Number: | 2447165 |
| Chromosome: | 9 |
| Deletion (size): | -13539bp+1bp |
| Research Areas: | nervous system,vision/eye,Physiological system,reproductive system,endocrine/exocrine glands,Cell biology,cellular,Cell localization,Cytoplasmic vesicle,endosome,Organelles membrane |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T013922.Cmtm6 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Suppression of tumor or host intrinsic CMTM6 drives antitumor cytotoxicity in a PD-L1 independent manner. Cancer Immunology Research (2023)2. CMTM6 maintains B cell-intrinsic CD40 expression to regulate anti-tumor immunity. bioRxiv (2024) |
| Gene Family: | CKLF like MARVEL transmembrane domain containing |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.