C57BL/6JGpt-Sarm1em1Cd5063/Gpt
Sarm1-KO|Strain NO.T014509
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Sarm1em1Cd5063/Gpt |
| Strain Number: | T014509 |
| Official Symbol: | Sarm1 |
| Strain Strategy: | T014509.Sarm1 Cas9-KO Strategy-EN.pdfT014509.Sarm1-KO strain info.pdf |
| Official Full Name: | sterile alpha and HEAT/Armadillo motif containing 1 |
| Also Known As: | A830091I15Rik,C78606,MyD885,Sarm |
| NCBI Number: | 237868 |
| MGI Number: | 2136419 |
| Chromosome: | 11 |
| Deletion (size): | -5063bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,cell differentiation,mortality/aging,immune system,nervous system,synapse,Physiological system,hematopoietic system,Cell biology,Cell death,Cytoskeleton,Mitochondrial research,cellular,cytomembrane,Molecular biology,Signal Transduction,hydrolytic enzyme |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T014509.Sarm1 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. SARM1 deletion inhibits astrogliosis and BBB damage through Jagged-1/Notch-1/NF-κB signaling to improve neurological function after ischemic stroke. Neurobiol Dis (2025) |
| Gene Family: | Armadillo like helical domain containingSterile alpha motif domain containingTIR domain containing |