C57BL/6JGpt-Prkcaem1Cd5428/Gpt
Mouse Model: Prkca-KO
Strain Number: T027858
Knockout (KO)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Prkcaem1Cd5428/Gpt |
| Strain Number: | T027858 |
| Official Symbol: | Prkca |
| Strain Strategy: | T027858.Prkca Cas9-KO Strategy-EN.pdf |
| Official Full Name: | protein kinase C, alpha |
| Also Known As: | AI875142,Pkca |
| NCBI Number: | 18750 |
| MGI Number: | 97595 |
| Chromosome: | 11 |
| Deletion (size): | -5428bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,Tumor research,nervous system,synapse,Physiological system,integument,cardiovascular system,Muscle ,Cell biology,Cell Proliferation,Cell death,Mitochondrial research,cellular,Cell localization,endoplasmic reticulum,cell nucleus,Organelles membrane,Molecular biology,Signal Transduction,transferase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T027858.Prkca Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Platelet Glycoprotein Ibα Cytoplasmic Tail Exacerbates Thrombosis During Bacterial Sepsis. Int J Mol Sci (2024)2. The role of protein kinase C and the glycoprotein Ibα cytoplasmic tail in anti-glycoprotein Ibα antibody-induced platelet apoptosis and thrombocytopenia. Thromb Res (2024) |
| Gene Family: | AGC family kinasesC2 domain containing protein kinasesMicroRNA protein coding host genes |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.