C57BL/6JGpt-Smoxem3Cd1243/Gpt

Mouse Model: Smox-KO
Strain Number: T027342

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Smoxem3Cd1243/Gpt
Strain Number: T027342
Official Symbol: Smox
Strain Strategy: T027342.Smox Cas9-KO Strategy-EN.pdf
Official Full Name: spermine oxidase
Also Known As: B130066H01Rik,PAO,PAOh1,SMO
NCBI Number: 228608
MGI Number: 2445356
Chromosome: 2
Deletion (size): -1243bp
Research Areas: Metabolic research,Developmental Biology,immune system,digestive/alimentary system,renal/urinary system,Physiological system,homeostasis/metabolism,Cell biology,Molecular biology,cellular,embryo,mortality/aging,cell nucleus,cytomembrane,oxidordeuctase
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T027342.Smox Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. The Spermine Oxidase/Spermine Axis Coordinates ATG5-Mediated Autophagy to Orchestrate Renal Senescence and Fibrosis. Advanced Science (2024)

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.