C57BL/6JGpt-Hoxa5em1Cflox/Gpt
Hoxa5-flox|Strain NO.T018353
Conditional knockout (cKO)
![](https://oss.gempharmatech.com/upload/20221109/detail-page2_06.jpg)
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BASIC INFORMATION
Strain Name: | C57BL/6JGpt-Hoxa5em1Cflox/Gpt |
Strain Number: | T018353 |
Official Symbol: | Hoxa5 |
Strain Strategy: | T018353.Hoxa5 Cas9-CKO Strategy-EN.pdf |
Official Full Name: | homeobox A5 |
Also Known As: | Hox-1.3 |
NCBI Number: | 15402 |
MGI Number: | 96177 |
Chromosome: | 6 |
Distance Between Two Loxps: | 1684bp |
Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,hearing/ear,Physiological system,skeleton,craniofacial ,respiratory system,reproductive system,digestive/alimentary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cell nucleus,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Conditional knockout (cKO) |
Genotyping Protocols: | T018353.Hoxa5 Genotyping Protocol(CKO).pdf |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. Hypermethylation leads to the loss of HOXA5, resulting in JAG1 expression and NOTCH signaling contributing to kidney fibrosis |
Gene Family: | HOXL subclass homeoboxes |