C57BL/6JGpt-Hoxa5em1Cflox/Gpt
Hoxa5-flox|Strain NO.T018353
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Hoxa5em1Cflox/Gpt |
| Strain Number: | T018353 |
| Official Symbol: | Hoxa5 |
| Strain Strategy: | T018353.Hoxa5 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | homeobox A5 |
| Also Known As: | Hox-1.3 |
| NCBI Number: | 15402 |
| MGI Number: | 96177 |
| Chromosome: | 6 |
| Distance Between Two Loxps: | 1684bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,hearing/ear,Physiological system,skeleton,craniofacial ,respiratory system,reproductive system,digestive/alimentary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cell nucleus,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T018353.Hoxa5 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Hypermethylation leads to the loss of HOXA5, resulting in JAG1 expression and NOTCH signaling contributing to kidney fibrosis |
| Gene Family: | HOXL subclass homeoboxes |