C57BL/6JGpt-Zbtb16em1Cflox/Gpt
Mouse Model: Zbtb16-flox
Strain Number: T016043
Conditional knockout (cKO)


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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
Strain Name: | C57BL/6JGpt-Zbtb16em1Cflox/Gpt |
Strain Number: | T016043 |
Official Symbol: | Zbtb16 |
Strain Strategy: | T016043.Zbtb16 Cas9-CKO Strategy-EN.pdf |
Official Full Name: | zinc finger and BTB domain containing 16 |
Also Known As: | AI467657,PLZF,Zfp145,lu |
NCBI Number: | 235320 |
MGI Number: | 103222 |
Chromosome: | 9 |
Distance Between Two Loxps: | 1333bp |
Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,cell differentiation,immune system,Physiological system,skeleton,reproductive system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,cellular,cell nucleus,Organelles membrane,Molecular biology,DNA transcription,DNA binding protein |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Conditional knockout (cKO) |
Genotyping Protocols: | T016043.Zbtb16 Genotyping Protocol(CKO).pdf |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. PLZF-expressing CD4+ T cells promote tissue-resident memory T cells in breaking immune tolerance in allergic asthma via IL-15/IL-15Rα signaling. Cell Commun Signal (2025) |
Gene Family: | BTB domain containingZinc fingers C2H2-type |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.