C57BL/6JGpt-G3bp1em1Cflox/Gpt

Mouse Model: G3bp1-flox
Strain Number: T015955

Conditional knockout (cKO)

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With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-G3bp1em1Cflox/Gpt
Strain Number: T015955
Official Symbol: G3bp1
Strain Strategy: T015955.G3bp1 Cas9-CKO Strategy-EN.pdf
Official Full Name: GTPase activating protein (SH3 domain) binding protein 1
Also Known As: AI849976,B430204O07,C87777,G3bp,mKIAA4115
NCBI Number: 27041
MGI Number: 1351465
Chromosome: 11
Distance Between Two Loxps: 1598bp
Research Areas: Developmental Biology,embryo,growth/size/body,mortality/aging,nervous system,vision/eye,Physiological system,cardiovascular system,skeleton,craniofacial ,respiratory system,limbs/digits/tail,Cell biology,cellular,cell nucleus,Molecular biology,Signal Transduction,DNA binding protein,hydrolytic enzyme,RNA binding protein
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T015955.G3bp1 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication. Journal of Virology (2022)
Gene Family: EndoribonucleasesRNA binding motif containing

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.