C57BL/6JGpt-Npc2em1Cflox/Gpt

Mouse Model: Npc2-flox
Strain Number: T015267

Conditional knockout (cKO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Npc2em1Cflox/Gpt
Strain Number: T015267
Official Symbol: Npc2
Strain Strategy: T015267.Npc2 Cas9-CKO Strategy-EN.pdf
Official Full Name: NPC intracellular cholesterol transporter 2
Also Known As: 2700012J19Rik,AA408070,AU045843,HE1
NCBI Number: 67963
MGI Number: 1915213
Chromosome: 12
Distance Between Two Loxps: 8408bp
Research Areas: Metabolic research,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,growth/size/body,mortality/aging,immune system,nervous system,behavior/neurological,Physiological system,cardiovascular system,respiratory system,digestive/alimentary system,liver/biliary system,endocrine/exocrine glands,hematopoietic system,Cell biology,cellular,Cell localization,endoplasmic reticulum,Molecular biology,Lipid binding protein,transporter,Niemann-Pick Disease
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T015267.Npc2 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Gene Family: MicroRNA protein coding host genes

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.