C57BL/6JGpt-Igf2bp1em1Cflox/Gpt

Mouse Model: Igf2bp1-flox
Strain Number: T015197

Conditional knockout (cKO)

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With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Igf2bp1em1Cflox/Gpt
Strain Number: T015197
Official Symbol: Igf2bp1
Strain Strategy: T015197.Igf2bp1 Cas9-CKO Strategy-EN.pdf
Official Full Name: insulin-like growth factor 2 mRNA binding protein 1
Also Known As: AL024068,AW549074,CRD-BP,Crdbp,D030026A21Rik,D11Moh40e,D11Moh45,IMP-1,IMP1,Neilsen,ZBP-1,Zbp1,mir-3063
NCBI Number: 140486
MGI Number: 1890357
Chromosome: 11
Distance Between Two Loxps: 3887bp
Research Areas: Metabolic research,Protein metabolism,homeostasis/metabolism,Developmental Biology,embryo,growth/size/body,mortality/aging,immune system,nervous system,behavior/neurological,synapse,Physiological system,skeleton,craniofacial ,Muscle ,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,cellular,Cell localization,cell nucleus,Molecular biology,RNA binding protein
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T015197.Igf2bp1 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. RNA-binding protein IGF2BP1 is required for spermatogenesis in an age-dependent manner. Commun Biol (2024)
Gene Family: RNA binding motif containing

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GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.