C57BL/6JGpt-Sirt4em13Cd1976/Gpt
Sirt4-KO|Strain NO.T011568
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
Strain Name: | C57BL/6JGpt-Sirt4em13Cd1976/Gpt |
Strain Number: | T011568 |
Official Symbol: | Sirt4 |
Strain Strategy: | T011568.Sirt4 Cas9-KO Strategy-EN.pdf |
Official Full Name: | sirtuin 4 |
Also Known As: | 4930596O17Rik |
NCBI Number: | 75387 |
MGI Number: | 1922637 |
Chromosome: | 5 |
Deletion (size): | -1976bp |
Research Areas: | Metabolic research,Protein metabolism,homeostasis/metabolism,Lipid Metabolism,nervous system,behavior/neurological,Cell biology,Cell death,Mitochondrial research,cellular,Cell localization,cytomembrane,Molecular biology,Signal Transduction,hydrolytic enzyme,transferase |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Knockout (KO) |
Genotyping Protocols: | T011568.Sirt4 Genotyping Protocol(KO).pdf |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. Ketogenic diet-produced beta-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy |
Gene Family: | Sirtuins |