C57BL/6JGpt-Sirt4em13Cd1976/Gpt

Sirt4-KO|Strain NO.T011568

Knockout (KO)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Sirt4em13Cd1976/Gpt
Strain Number: T011568
Official Symbol: Sirt4
Strain Strategy: T011568.Sirt4 Cas9-KO Strategy-EN.pdf
Official Full Name: sirtuin 4
Also Known As: 4930596O17Rik
NCBI Number: 75387
MGI Number: 1922637
Chromosome: 5
Deletion (size): -1976bp
Research Areas: Metabolic research,Protein metabolism,homeostasis/metabolism,Lipid Metabolism,nervous system,behavior/neurological,Cell biology,Cell death,Mitochondrial research,cellular,Cell localization,cytomembrane,Molecular biology,Signal Transduction,hydrolytic enzyme,transferase
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T011568.Sirt4 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Ketogenic diet-produced beta-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy
Gene Family: Sirtuins