C57BL/6JGpt-Clec7aem13Cd5299/Gpt

Mouse Model: Clec7a-KO
Strain Number: T011442

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Clec7aem13Cd5299/Gpt
Strain Number: T011442
Official Symbol: Clec7a
Strain Strategy: T011442.Clec7a Cas9-KO Strategy-EN.pdf
Official Full Name: C-type lectin domain family 7, member a
Also Known As: BGR,Clecsf12,beta-GR
NCBI Number: 56644
MGI Number: 1861431
Chromosome: 6
Deletion (size): -5299bp
Research Areas: Metabolic research,homeostasis/metabolism,Developmental Biology,mortality/aging,immune system,Physiological system,respiratory system,digestive/alimentary system,hematopoietic system,Cell biology,cellular,Cell localization,Organelles membrane,Molecular biology,Signal Transduction
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T011442.Clec7a Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-beta1 secretion. Cell Mol Life Sci (2023)
Gene Family: C-type lectin domain containingCD moleculesScavenger receptors

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.