C57BL/6JGpt-Piezo1em1Cflox/Gpt
Mouse Model: Piezo1-flox
Strain Number: T009627
Conditional knockout (cKO)
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With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Piezo1em1Cflox/Gpt |
| Strain Number: | T009627 |
| Official Symbol: | Piezo1 |
| Strain Strategy: | Log in to read more |
| Official Full Name: | piezo-type mechanosensitive ion channel component 1 |
| Also Known As: | 9630020g22,Fam38a,mKIAA0233 |
| NCBI Number: | 234839 |
| MGI Number: | 3603204 |
| Chromosome: | 8 |
| Distance Between Two Loxps: | 10787bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,embryo,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,Physiological system,integument,cardiovascular system,renal/urinary system,hematopoietic system,limbs/digits/tail,Cell biology,cellular,Cell localization,endoplasmic reticulum,Organelles membrane,Molecular biology,transporter |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | Log in to read more |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Mechanical force receptor Piezo1 regulates TH9 cell differentiation. Cell Reports (2024)2. PIEZO1 activation enhances myogenesis and mitigates muscle degeneration in rotator cuff tear. Regenerative Therapy (2024)3. Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear. Journal of cachexia, sarcopenia and muscle (2025) |
| Gene Family: | MicroRNA protein coding host genes |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.