C57BL/6JGpt-Piezo1em1Cflox/Gpt
Piezo1-flox|Strain NO.T009627
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Piezo1em1Cflox/Gpt |
| Strain Number: | T009627 |
| Official Symbol: | Piezo1 |
| Strain Strategy: | T009627.Piezo1 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | piezo-type mechanosensitive ion channel component 1 |
| Also Known As: | 9630020g22,Fam38a,mKIAA0233 |
| NCBI Number: | 234839 |
| MGI Number: | 3603204 |
| Chromosome: | 8 |
| Distance Between Two Loxps: | 10787bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,embryo,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,Physiological system,integument,cardiovascular system,renal/urinary system,hematopoietic system,limbs/digits/tail,Cell biology,cellular,Cell localization,endoplasmic reticulum,Organelles membrane,Molecular biology,transporter |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T009627.Piezo1 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Mechanical force receptor Piezo1 regulates TH9 cell differentiation. Cell Reports (2024)2. PIEZO1 activation enhances myogenesis and mitigates muscle degeneration in rotator cuff tear. Regenerative Therapy (2024)3. Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear. Journal of cachexia, sarcopenia and muscle (2025) |
| Gene Family: | MicroRNA protein coding host genes |