C57BL/6JGpt-Grin2bem1Cflox/Gpt
Grin2b-flox|Strain NO.T009537
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Grin2bem1Cflox/Gpt |
| Strain Number: | T009537 |
| Official Symbol: | Grin2b |
| Strain Strategy: | T009537.Grin2b Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | glutamate receptor, ionotropic, NMDA2B (epsilon 2) |
| Also Known As: | AW490526,GluN2B,GluRepsilon2,NR2B,Nmdar2b |
| NCBI Number: | 14812 |
| MGI Number: | 95821 |
| Chromosome: | 6 |
| Distance Between Two Loxps: | 2300bp |
| Research Areas: | Metabolic research,Developmental Biology,nervous system,Signal Transduction,Cell death,Protein metabolism,homeostasis/metabolism,behavior/neurological,Cell biology,Molecular biology,cellular,growth/size/body,mortality/aging,Cell localization,Cytoplasmic vesicle,endosome,Organelles membrane,synapse,transporter |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T009537.Grin2b Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain2. Activation of the N-methyl-D-aspartate receptor contributes to orofacial neuropathic and inflammatory allodynia by facilitating calcium-calmodulin-dependent protein kinase II phosphorylation in mice |
| Gene Family: | Glutamate ionotropic receptor NMDA type subunits |