C57BL/6JGpt-Prmt1em1Cflox/Gpt

Mouse Model: Prmt1-flox
Strain Number: T008182

Conditional knockout (cKO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Prmt1em1Cflox/Gpt
Strain Number: T008182
Official Symbol: Prmt1
Strain Strategy: T008182.Prmt1 Cas9-CKO Strategy-EN.pdf
Official Full Name: protein arginine N-methyltransferase 1
Also Known As: 6720434D09Rik,AW214366,Hrmt1l2,Mrmt1
NCBI Number: 15469
MGI Number: 107846
Chromosome: 7
Distance Between Two Loxps: 2200bp
Research Areas: Metabolic research,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,embryo,mortality/aging,Physiological system,reproductive system,Cell biology,Cell Proliferation,cellular,cell nucleus,Molecular biology,Signal Transduction,DNA binding protein,transferase
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T008182.Prmt1 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility. Nucleic Acids Res (2023)
Gene Family: MicroRNA protein coding host genesProtein arginine methyltransferases

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.