C57BL/6JGpt-Lmnaem1Cflox/Gpt
Lmna-flox|Strain NO.T007824
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Lmnaem1Cflox/Gpt |
| Strain Number: | T007824 |
| Official Symbol: | Lmna |
| Strain Strategy: | T007824.Lmna Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | lamin A |
| Also Known As: | Dhe |
| NCBI Number: | 16905 |
| MGI Number: | 96794 |
| Chromosome: | 3 |
| Distance Between Two Loxps: | 3200bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,hearing/ear,behavior/neurological,Physiological system,integument,pigmentation,cardiovascular system,skeleton,craniofacial ,Muscle ,respiratory system,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,Cytoskeleton,cellular,Cell localization,cell nucleus,cytomembrane,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T007824.Lmna Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism |
| Gene Family: | Lamins |