C57BL/6JGpt-P2rx7em1Cflox/Gpt
Mouse Model: P2rx7-flox
Strain Number: T009615
Conditional knockout (cKO)
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With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-P2rx7em1Cflox/Gpt |
| Strain Number: | T009615 |
| Official Symbol: | P2rx7 |
| Strain Strategy: | Log in to read more |
| Official Full Name: | purinergic receptor P2X, ligand-gated ion channel, 7 |
| Also Known As: | AI467586,P2X(7),P2X7R |
| NCBI Number: | 18439 |
| MGI Number: | 1339957 |
| Chromosome: | 5 |
| Distance Between Two Loxps: | 1300bp |
| Research Areas: | Metabolic research,Developmental Biology,immune system,integument,nervous system,Signal Transduction,skeleton,vision/eye,Cell Proliferation,Cell death,Protein metabolism,Glucose metabolism,Physiological system,homeostasis/metabolism,behavior/neurological,Cell biology,Molecular biology,cellular,growth/size/body,hematopoietic system,limbs/digits/tail,Cell localization,Lipid Metabolism,cell nucleus,cytomembrane,Organelles membrane,synapse,Lipid binding protein,transporter |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | Log in to read more |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. The P2X7R/NLRP3 inflammasome axis suppresses enthesis regeneration through inflammatory and metabolic macrophage-stem cell cross-talk. Sci Adv (2025) |
| Gene Family: | Purinergic receptors P2X |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.