C57BL/6JGpt-Ythdf1em1Cflox/Gpt
Ythdf1-flox|Strain NO.T009315
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
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- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Ythdf1em1Cflox/Gpt |
| Strain Number: | T009315 |
| Official Symbol: | Ythdf1 |
| Strain Strategy: | T009315. Ythdf1 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | YTH N6-methyladenosine RNA binding protein 1 |
| Also Known As: | 2210410K23Rik,8030473O16 |
| NCBI Number: | 228994 |
| MGI Number: | 1917431 |
| Chromosome: | 2 |
| Distance Between Two Loxps: | 1114bp |
| Research Areas: | Metabolic research,Protein metabolism,Developmental Biology,cell differentiation,Physiological system,cardiovascular system,Cell biology,cellular,Molecular biology,Signal Transduction,RNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T009315.Ythdf1 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. The YTHDF1-TRAF6 pathway regulates the neuroinflammatory response and contributes to morphine tolerance and hyperalgesia in the periaqueductal gray2. YTHDF1 mitigates acute kidney injury via safeguarding m(6)A-methylated mRNAs in stress granules of renal tubules3. YTHDF1 in periaqueductal gray inhibitory neurons contributes to morphine withdrawal responses in mice |