Fgf4-flox|Strain NO.T009264

Conditional knockout (cKO)

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Strain Name: C57BL/6JGpt-Fgf4em1Cflox/Gpt
Strain Number: T009264
Official Symbol: Fgf4
Strain Strategy: T009264.Fgf4 Cas9-CKO Strategy-EN.pdf
Official Full Name: fibroblast growth factor 4
Also Known As: Fgf-4,Fgfk,HBGF-4,Hst1,Hstf-1,KS3,hst,hst-1,kFGF
NCBI Number: 14175
MGI Number: 95518
Chromosome: 7
Distance Between Two Loxps: 15000bp
Research Areas: Metabolic research,Protein metabolism,Developmental Biology,cell differentiation,embryo,growth/size/body,mortality/aging,nervous system,vision/eye,Physiological system,skeleton,reproductive system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,cellular,Molecular biology,Signal Transduction,DNA transcription
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T009264.Fgf4 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. FGF4 protects the liver from nonalcoholic fatty liver disease by activating the AMP-activated protein kinase-Caspase 6 signal axis2. A non-mitogenic FGF4 analog alleviates non-alcoholic steatohepatitis through an AMPK-dependent pathway
Gene Family: Fibroblast growth factor familyReceptor ligands