C57BL/6JGpt-Nat10em1Cflox/Gpt
Mouse Model: Nat10-flox
Strain Number: T007971
Conditional knockout (cKO)
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- Quantity: - +
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With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Nat10em1Cflox/Gpt |
| Strain Number: | T007971 |
| Official Symbol: | Nat10 |
| Strain Strategy: | T007971.Nat10 Cas9-CKO Strategy-EN .pdf |
| Official Full Name: | N-acetyltransferase 10 |
| Also Known As: | AI429152 |
| NCBI Number: | 98956 |
| MGI Number: | 2138939 |
| Chromosome: | 2 |
| Distance Between Two Loxps: | 2400bp |
| Research Areas: | Metabolic research,Protein metabolism,homeostasis/metabolism,immune system,Physiological system,hematopoietic system,Cell biology,cellular,cell nucleus,Molecular biology,RNA binding protein,transferase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T007971.Nat10 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Nat Commun (2023)2. The Cytidine N-Acetyltransferase NAT10 Promotes Thalamus Hemorrhage-Induced Central Poststroke Pain by Stabilizing Fn14 Expression in Thalamic Neurons. Molecular Neurobiology (2024)3. Improvement of MASLD and MASH by suppression of hepatic N-acetyltransferase 10. Molecular Metabolism (2024)4. NAT10-mediated mRNA N4-acetylcytidine reprograms serine metabolism to drive leukaemogenesis and stemness in acute myeloid leukaemia. Nat Cell Biol (2024) |
| Gene Family: | GCN5 related N-acetyltransferases |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.