C57BL/6JGpt-Cxcr3em14Cd2458/Gpt
Cxcr3-KO|Strain NO.T006559
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Cxcr3em14Cd2458/Gpt |
| Strain Number: | T006559 |
| Official Symbol: | Cxcr3 |
| Strain Strategy: | T006559.Cxcr3 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | chemokine (C-X-C motif) receptor 3 |
| Also Known As: | Cd183,Cmkar3 |
| NCBI Number: | 12766 |
| MGI Number: | 1277207 |
| Chromosome: | X |
| Deletion (size): | -2458bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,mortality/aging,immune system,Tumor research,Physiological system,cardiovascular system,respiratory system,renal/urinary system,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cellular,Cell localization,Organelles membrane,Molecular biology,Signal Transduction,DNA transcription |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T006559.Cxcr3 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. CXCL10 conditions alveolar macrophages within the premetastatic niche to promote metastasis2. METTL3-mediated N6-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication3. Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms |
| Gene Family: | C-X-C motif chemokine receptorsCD molecules |