C57BL/6JGpt-C5ar1em3Cd3133/Gpt
C5ar1-KO|Strain NO.T006107
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-C5ar1em3Cd3133/Gpt |
| Strain Number: | T006107 |
| Official Symbol: | C5ar1 |
| Strain Strategy: | T006107.C5ar1 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | complement component 5a receptor 1 |
| Also Known As: | C5aR,C5r1,Cd88,D7Msu1 |
| NCBI Number: | 12273 |
| MGI Number: | 88232 |
| Chromosome: | 7 |
| Research Areas: | Metabolic research,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,mortality/aging,immune system,nervous system,vision/eye,Physiological system,skeleton,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cellular,Cytoplasmic vesicle,Organelles membrane,Molecular biology,Signal Transduction,DNA transcription |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T006107.C5ar1 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization |
| Gene Family: | CD moleculesComplement component GPCRsComplement system regulators and receptors |