C57BL/6JGpt-C3ar1em6Cd4816/Gpt
C3ar1-KO|Strain NO.T006106
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-C3ar1em6Cd4816/Gpt |
| Strain Number: | T006106 |
| Official Symbol: | C3ar1 |
| Strain Strategy: | T006106.C3ar1 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | complement component 3a receptor 1 |
| Also Known As: | AZ3B,C3AR,HNFAG09 |
| NCBI Number: | 12267 |
| MGI Number: | 1097680 |
| Chromosome: | 6 |
| Deletion (size): | -4816bp |
| Research Areas: | Metabolic research,adipose tissue,homeostasis/metabolism,Developmental Biology,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,Physiological system,skeleton,respiratory system,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell Proliferation,cellular,Organelles membrane,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T006106.C3ar1 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. C3aR contributes to unilateral ureteral obstruction-induced renal interstitial fibrosis via the activation of the NLRP3 inflammasome2. C3a/C3aR synergies with TGF-beta to promote epithelial-mesenchymal transition of renal tubular epithelial cells via the activation of the NLRP3 inflammasome |
| Gene Family: | Complement component GPCRsComplement system regulators and receptors |