C57BL/6JGpt-Tg(APP,hPSEN1)48/Gpt
FAD2T(APP/PS1)|Strain NO.T005625
Transgenic (Tg)
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- Quantity: - +
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Tg(APP,hPSEN1)48/Gpt |
| Strain Number: | T005625 |
| Official Symbol: | App,Psen1 |
| Strain Strategy: | T005625.FAD2T(APP PS1) strain info.pdf |
| Official Full Name: | amyloid beta (A4) precursor protein,presenilin 1 |
| Also Known As: | Ag,Abpp,Adap,Cvap,Abeta,betaApp,E030013M08Rik,PS1,Ad3h,PS-1,S182 |
| NCBI Number: | 1182019164 |
| Research Areas: | Disease Models,Neurodegenerative diseases,Alzheimer's disease |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Transgenic (Tg) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Impairments of GABAergic transmission in hippocampus mediate increased susceptibility of epilepsy in the early stage of Alzheimer's disease2. Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer's disease |