BALB/cJGpt-Pdcd1em1Cin(hPDCD1)Lag3em1Cin(hLAG3)/Gpt
BALB/c-hPD1/hLAG3|Strain NO.T004622
Knockin (KI)
![](https://oss.gempharmatech.com/upload/20221109/detail-page2_06.jpg)
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BASIC INFORMATION
Strain Name: | BALB/cJGpt-Pdcd1em1Cin(hPDCD1)Lag3em1Cin(hLAG3)/Gpt |
Strain Number: | T004622 |
Official Symbol: | Pdcd1,PDCD1,Lag3,LAG3 |
Strain Strategy: | T004622.BALB_c-hPD1_hLAG3 strain info.pdf |
Official Full Name: | programmed cell death 1,lymphocyte-activation gene 3,lymphocyte activating 3 |
Also Known As: | PD-1,Pdc1,Ly101,PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,Ly66,CD223,LAG-3 |
NCBI Number: | 185665133167683902 |
Research Areas: | Humanized model,Gene humanization model,Humanization of tumor targets |
Strain Background: | [N000020] BALB/cJGpt |
Modification Type: | Knockin (KI) |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. A novel anti-LAG-3/TIGIT bispecific antibody exhibits potent anti-tumor efficacy in mouse models as monotherapy or in combination with PD-1 antibody |