C57BL/6JGpt-Krasem1Cin(loxP-stop-loxP-G12D)/Gpt
Mouse Model: B6-Kras-LSL-G12D
Strain Number: T004551
Knockin (KI)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Krasem1Cin(loxP-stop-loxP-G12D)/Gpt |
| Strain Number: | T004551 |
| Official Symbol: | Kras |
| Strain Strategy: | T004551.B6-Kras G12D strain info.pdf |
| Official Full Name: | Kirsten rat sarcoma viral oncogene homolog |
| Also Known As: | AI929937,K-Ras,K-Ras 2,K-ras,Ki-ras,Kras-2,Kras2,c-K-ras,c-Ki-ras,p21B,ras |
| NCBI Number: | 16653 |
| MGI Number: | 96680 |
| Chromosome: | 6 |
| Research Areas: | Disease Models,Tumor model,Spontaneous tumor |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockin (KI) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Heparan sulfate regulates myofibroblast heterogeneity and function to mediate niche homeostasis during alveolar morphogenesis. Nature communications (2025)2. RASON promotes KRASG12C-driven tumor progression and immune evasion in non-small cell lung cancer. J Exp Clin Cancer Res (2025) |
| Gene Family: | RAS type GTPase family |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.