C57BL/6JGpt-H11em1Cin(Alb-iCre)/Gpt

Mouse Model: H11-Alb-iCre
Strain Number: T003814

Knockin (KI)

  • Product Type:
  • Quantity: - +
  • Sex:
  • Age:
  • Genotype:

GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-H11em1Cin(Alb-iCre)/Gpt
Strain Number: T003814
Official Symbol: Alb,iCre
Strain Strategy: Log in to read more
Official Full Name: albumin
Also Known As: Alb-1,Alb1,BCL002
NCBI Number: 11657
MGI Number: 87991
Chromosome: 11
Research Areas: Tool Mice,Cre/Dre
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockin (KI)
Genotyping Protocols: Log in to read more
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. FGF4 protects the liver from nonalcoholic fatty liver disease by activating the AMP-activated protein kinase-Caspase 6 signal axis. Hepatology (2022)2. Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression. Cell Metab (2022)3. Mettl3-mediated mRNA m(6)A modification controls postnatal liver development by modulating the transcription factor Hnf4a. Nat Commun (2022)4. Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis. Blood (2024)5. Improvement of MASLD and MASH by suppression of hepatic N-acetyltransferase 10. Molecular Metabolism (2024)6. Loss of hepatocyte Usp53 protects mice from a form of xenobiotic-induced liver injury. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2024)7. Gut microbiota-produced vitamin B6 mitigates alcohol-associated liver disease by attenuating hepatic oxidative stress damage. Hepatol Commun (2024)8. NLRP3 inflammasome constrains liver regeneration through impairing MerTK-mediated macrophage efferocytosis. Science advances (2025)9. Hepatic factor MANF drives hepatocytes reprogramming by detaining cytosolic CK19 in intrahepatic cholangiocarcinoma. Cell death and differentiation (2025)10. SNORA74A Drives Self-Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling. Adv Sci (Weinh) (2025)11. L-methionine promotes CD8+ T cells killing hepatocellular carcinoma by inhibiting NR1I2/PCSK9 signaling. Neoplasia (2025)12. Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups. Cancer Cell (2025)13. Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activation during hepatic fibrosis. Cell death & disease (2025)14. Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD-MASH Transition by Disrupting Carnitine Biosynthesis. Adv Sci (Weinh) (2025)15. DTL dose-dependent control of sex-dimorphic ferroptosis in liver ischemia reperfusion injury. Cell reports (2025)16. Sphingolipid synthesis in tumor-associated macrophages confers immunotherapy resistance in hepatocellular carcinoma. Science advances (2025)

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.