NOD/ShiLtJGpt-Prkdcem26Cd52Il2rgem26Cd22kitem1Cin(V831M)/Gpt
NCG-X|Strain NO.T003802
Point mutation (PM)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | NOD/ShiLtJGpt-Prkdcem26Cd52Il2rgem26Cd22kitem1Cin(V831M)/Gpt |
| Strain Number: | T003802 |
| Official Symbol: | Kit |
| Strain Strategy: | T003802.NCG-X strain info.pdf |
| Official Full Name: | KIT proto-oncogene receptor tyrosine kinase |
| Also Known As: | Bs,CD117,Fdc,Gsfsco1,Gsfsco5,Gsfsow3,SCO1,SCO5,SOW3,Ssm,Tr-kit,W,c-KIT |
| NCBI Number: | 16590 |
| MGI Number: | 96677 |
| Chromosome: | 5 |
| Research Areas: | Humanized model,Humanization of the immune system,Immunodeficiency |
| Strain Background: | [N000235] NOD/ShiLtJGpt |
| Modification Type: | Point mutation (PM) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia2. Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC3. Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR-RUNX14. Tumor-derived exosomal linc00881 induces lung fibroblast activation and promotes osteosarcoma lung migration |
| Gene Family: | CD moleculesImmunoglobulin like domain containingReceptor tyrosine kinases |