C57BL/6JGpt-Hectd1em1Cd1306/Gpt

Mouse Model: Hectd1-KO
Strain Number: T003879

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Hectd1em1Cd1306/Gpt
Strain Number: T003879
Official Symbol: Hectd1
Strain Strategy: T003879.Hectd1 Cas9-KO Strategy-EN.pdf
Official Full Name: HECT domain E3 ubiquitin protein ligase 1
Also Known As: A630086P08Rik,AI844876,b2b327Clo,opm
NCBI Number: 207304
MGI Number: 2384768
Chromosome: 12
Deletion (size): -1306bp
Research Areas: Metabolic research,Developmental Biology,integument,cardiovascular system,nervous system,skeleton,vision/eye,Protein metabolism,Physiological system,cell differentiation,Molecular biology,craniofacial ,embryo,growth/size/body,mortality/aging,pigmentation,transferase
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T003879.Hectd1 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis. Cell & bioscience (2021)
Gene Family: Ankyrin repeat domain containingArmadillo like helical domain containingHECT domain containing

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.