C57BL/6JGpt-Sucnr1em2Cd2765/Gpt

Mouse Model: Sucnr1-KO
Strain Number: T003408

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Sucnr1em2Cd2765/Gpt
Strain Number: T003408
Official Symbol: Sucnr1
Strain Strategy: T003408. Sucnr1 Cas9-KO Strategy-EN.pdf
Official Full Name: succinate receptor 1
Also Known As: Gpr91
NCBI Number: 84112
MGI Number: 1934135
Chromosome: 3
Deletion (size): -2765bp
Research Areas: Metabolic research,Protein metabolism,homeostasis/metabolism,immune system,Physiological system,renal/urinary system,hematopoietic system,Cell biology,cellular,Cell localization,Organelles membrane,Molecular biology,Signal Transduction
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T003408.Sucnr1 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Hypoxic dental pulp stem cells-released succinate promotes osteoclastogenesis and root resorption. Int J Med Sci (2024)2. Compressive force-induced succinate production via metabolic reprogramming in periodontal ligament cells promotes orthodontic tooth movement. Progress in orthodontics (2025)
Gene Family: Succinate receptor

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.