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C57BL/6JGpt-
Apc
em1Cin(Min)
/Gpt
APC-min|Strain NO.T001457
Point mutation (PM)
Product Type:
Live Mouse
Sperm
Frozen Embryo
Quantity:
-
+
Sex:
Male
Female
Age:
1 weeks
2 weeks
3 weeks
4 weeks
5 weeks
6 weeks
7 weeks
8 weeks
9 weeks
10 weeks
11 weeks
12 weeks
13 weeks
14 weeks
15 weeks
16 weeks
17 weeks
18 weeks
19 weeks
20 weeks
21 weeks
22 weeks
23 weeks
24 weeks
25 weeks
26 weeks
27 weeks
28 weeks
29 weeks
30 weeks
>30 weeks
Genotype:
(Apc)mut/wt
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BASIC INFORMATION
Strain Name:
C57BL/6JGpt-
Apc
em1Cin(Min)
/Gpt
Strain Number:
T001457
Official Symbol:
Apc
Strain Strategy:
T001457.Apc-min strain info.pdf
Official Full Name:
APC, WNT signaling pathway regulator
Also Known As:
AI047805,AU020952,AW124434,CC1,Min,mAPC
NCBI Number:
11789
MGI Number:
88039
Chromosome:
18
Research Areas:
Disease Models,Tumor model,Spontaneous tumor
Strain Background:
[N000013] C57BL/6JGpt
Modification Type:
Point mutation (PM)
Inventory Status:
Live,Cryopreserved
Sale Status:
IF (Available for Distribution)
Health Status:
Specific pathogen free (SPF)
Health Report:
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Publications:
1. Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors
2. Probiotic strain Lactobacillus plantarum YYC-3 prevents colon cancer in mice by regulating the tumour microenvironment
3. Gambogenic acid induces Noxa-mediated apoptosis in colorectal cancer through ROS-dependent activation of IRE1α/JNK
4. Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway
5. The protection of crocin against ulcerative colitis and colorectal cancer via suppression of NF-κB-mediated inflammation
6. Effect of pristimerin on apoptosis through activation of ROS/endoplasmic reticulum (ER) stress-mediated noxa in colorectal cancer
7. ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function
8. Calf Thymus Polypeptide Restrains the Growth of Colorectal Tumor via Regulating the Intestinal Microbiota-Mediated Immune Function
9. IL-36γ and IL-36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell-Matrix Adhesion Network and Wnt Signaling
10. p53 promotes peroxisomal fatty acid beta-oxidation to repress purine biosynthesis and mediate tumor suppression
11. Overdose intake of Neu5Gc triggers colorectal inflammation and alters liver metabolism
12. A novel antidiuretic hormone governs tumour-induced renal dysfunction
Gene Family:
Armadillo repeat containing
Protein phosphatase 1 regulatory subunits
0
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