Detail information of PDX-SC00352

• Growth Properties

Fig 1. Growth Properties

• Pathology Diagnosis

Tumor size: The visible size of the small curvature of the gastric antrum is 4.6 cm × 3.7 cm × 1.7 cm ulcerative mass tumor with a gray white section, solid, medium texture, invasion of the entire layer, and unclear boundaries.

Histological type: Adenocarcinoma（Diffuse patchy arrangement, infiltrating growth, cellular atypia, large nuclei, and frequent nuclear division）.

Stage: T4aN3aM0.

Histological grading: Poorly differentiated.

IHC: CK-P (+). CK-L (-), CD20 (+), CD3 (+), Her-2 (2+), Ki-67 (hot spot positive rate 60%), SMA (+), Desmin (+), DOG (partial+), CD117 (partial+), CD34 (vascular+), S-100 (-), Ki-67 (positive rate<1%).

• Gene mutation in WES

Table 1. Gene mutation (Partial)