Detail information of PDX-PC00425

  • Growth Properties

图片2.png

Fig 1.  Growth Properties

  • Pathology Diagnosis

Tumor size: Tumor size: 2.5cm × 2cm × 1.7cm.

Histological type: Ductal adenocarcinoma(Pancreatic ductal adenocarcinoma. Infiltration of pancreatic parenchyma, peripancreatic adipose fiber connective tissue).

Histological grading: High histological differentiation: 10%; Differentiation in histology: 80%; Low histological differentiation: 10%.

  • Gene mutation in WES

Table 1. Gene mutation  (Partial)

Gene

Hgvs

Priority

EGFR

p.R468K

L

KRAS

p.G12V

H

ALK

p.K423R; p.K1491R; p.I393V; p.I1461V; p.D461E; p.D1529E

L

TP53

p.P33R; p.P72R
p.R43H; p.R136H; p.R175H; p.R16H

L

H

PTCH1

p.P1315L; p.P1314L; p.P1164L; p.P1249L; p.P1263L

L

BRCA1

p.E991G; p.E1038G; p.S1566G; p.S1613G; p.S509G; p.S1634G; p.P871L; p.P824L; p.K1183R; p.K1136R

L

BRCA2

p.N372H; p.V2466A

L

CSF1R

p.H362R

L

ERBB2

p.P1155A; p.P1140A; p.P1170A

M

FLT3

p.T227M

H