Detail information of PDX-PC00425
Growth Properties
Fig 1. Growth Properties
Pathology Diagnosis
Tumor size: Tumor size: 2.5cm × 2cm × 1.7cm.
Histological type: Ductal adenocarcinoma(Pancreatic ductal adenocarcinoma. Infiltration of pancreatic parenchyma, peripancreatic adipose fiber connective tissue).
Histological grading: High histological differentiation: 10%; Differentiation in histology: 80%; Low histological differentiation: 10%.
Gene mutation in WES
Table 1. Gene mutation (Partial)
Gene | Hgvs | Priority |
EGFR | p.R468K | L |
KRAS | p.G12V | H |
ALK | p.K423R; p.K1491R; p.I393V; p.I1461V; p.D461E; p.D1529E | L |
TP53 | p.P33R; p.P72R | L H |
PTCH1 | p.P1315L; p.P1314L; p.P1164L; p.P1249L; p.P1263L | L |
BRCA1 | p.E991G; p.E1038G; p.S1566G; p.S1613G; p.S509G; p.S1634G; p.P871L; p.P824L; p.K1183R; p.K1136R | L |
BRCA2 | p.N372H; p.V2466A | L |
CSF1R | p.H362R | L |
ERBB2 | p.P1155A; p.P1140A; p.P1170A | M |
FLT3 | p.T227M | H |