Detail information of PDX-LC00202
Growth Properties
Fig 1. Growth Properties
Pathology Diagnosis
Tumor size: Right lower lobe specimen: A mass at the hilum of the lung, approximately 6cm × 3.5cm × 3cm.
Histological type: Central type of lung with low differentiation.
Histological grading: Poorly differentiated.
Gene mutation in WES
Table 1. Gene mutation (Partial)
Gene | Hgvs | Priority |
PD-L1(CD274) | c.*93G>A | L |
ALK | p.I1461V; p.D1529E; p.K1491R | L |
TP53 | p.P33R; p.P72R | L H |
ATM | p.N1983S | L |
BRCA1 | p.E1038G; p.E991G; p.S1634G; p.S1613G; p.S509G; p.S1566G; p.K1183R; p.K1136R; p.P824L; p.P871L; p.E1038G; | L |
PDGFRA | p.S478P | L |
BRCA2 | p.N372H; p.V2466A | L |
CHEK2 | p.L15P; p.L279P; p.L236P; p.L236P | H |
ERBB2 | p.P1170A; p.P1140A | L |
IDH1 | p.Y208C | H |
FLT3 | p.T227M | L |
Gene fusion in RNA-seq
Table 2. Gene fusion
PDX ID | Gene 1_ Gene 2 |
LC00202 | TANGO2_TMEM41B |