Detail information of PDX- BLC00423
Growth Properties
Fig 1. Growth Properties
Pathology Diagnosis
Tumor size: Bladder size 12×10×4 cm. Incision of the bladder reveals a growing mass in the ring cavity, 7×5×1.6 cm in size.
Histological type: Invasive urothelial carcinoma (high grade).
Histological grading: High grade.
IHC: CK20 (minor+), CK7(+), P63 (+), Ki-67 (approximately 50%+), P53 (partial+).
Gene mutation results in WES sequencing
Table 1. Gene mutation results (Partial)
Gene | Hgvs | Priority |
ATM | p.R468K; p.R476K; p.R521K | H |
RET | p.G691S; p.G437S | L |
FLT3 | p.D7G; p.T227M | L |
FGFR3 | p.S249C | H |
EZH2 | p.D185H; p.D146H; p.D176H | L |